POT1 anticorps (Internal Region)
Aperçu rapide pour POT1 anticorps (Internal Region) (ABIN7216628)
Antigène
Voir toutes POT1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Fonction
- POT1 Polyclonal Antibody
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Specificité
- POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human POT1
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- POT1 (Protection of Telomeres 1 (POT1))
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Autre désignation
- POT1
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Sujet
- Rabbit Anti-POT1 Polyclonal Antibody,POT1, Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein,POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.,Protection of telomeres protein 1
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Poids moléculaire
- observerd band 70kDa
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ID gène
- 25913
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UniProt
- Q9NUX5
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Pathways
- Cycle Cellulaire, Telomere Maintenance
Antigène
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