PICK1 anticorps

N° du produit ABIN7230634

L’anticorps anti-PICK1 Polyclonal Lapin est utilisé pour la détection de PICK1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour PICK1 anticorps (ABIN7230634)

Antigène: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PICK1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PICK1 anticorps

Fonction: Rabbit Anti-PICK1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PICK1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human PICK1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PICK1

Antigène: PICK1 (Protein Interacting With Protein Kinase C, alpha 1 (PICK1))

Autre désignation: PICK1

Sujet: PRKCA-binding protein, Protein interacting with C kinase 1, Protein kinase C-alpha-binding proteinThe protein encoded by PICK1 gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 45kD

ID gène: 9463

UniProt: Q9NRD5