PTPN12 anticorps

N° du produit ABIN7230828

Cet anticorps Lapin Polyclonal détecte spécifiquement PTPN12 dans WB et ELISA. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour PTPN12 anticorps (ABIN7230828)

Antigène: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN12 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-PTPN12 anticorps

Fonction: PTN12 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of PTN12 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human PTN12 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PTPN12

Antigène: PTPN12 (Protein Tyrosine Phosphatase G1 (PTPN12))

Autre désignation: PTN12

Sujet: Rabbit Anti-PTN12 Polyclonal Antibody,Tyrosine-protein phosphatase non-receptor type 12, PTP-PEST, Protein-tyrosine phosphatase G1, PTPG1,PTPN12 (Protein Tyrosine Phosphatase, Non-Receptor Type 12) is a Protein Coding gene. Diseases associated with PTPN12 include Colorectal Cancer and Colonic Benign Neoplasm. Among its related pathways are DNA Damage and Signaling by ERBB2. The protein encoded by PTPN12 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility.,PTN12

Poids moléculaire: observerd band 85kDa

ID gène: 5782

UniProt: Q05209