PWWP2B anticorps (AA 240-320)

N° du produit ABIN7220034

Cet anticorps Lapin Polyclonal détecte spécifiquement PWWP2B dans WB, ELISA et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour PWWP2B anticorps (AA 240-320) (ABIN7220034)

Antigène: PWWP2B (PWWP Domain Containing 2B (PWWP2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PWWP2B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PWWP2B anticorps

Épitope: AA 240-320

Fonction: PWWP2B Polyclonal Antibody

Specificité: PWWP2B Polyclonal Antibody detects endogenous levels of PWWP2B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human PWWP2B at AA range: 240-320

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur PWWP2B

Antigène: PWWP2B (PWWP Domain Containing 2B (PWWP2B))

Autre désignation: PWWP2B

Sujet: Rabbit Anti-PWWP2B Polyclonal Antibody,PWWP2B, PWWP2, PWWP domain-containing protein 2B,PWWP2B (PWWP domain containing 2B) is a 590 amino acid protein that contains a PWWP domain which is involved in protein-protein interactions. The PWWP2B protein is phosphorylated upon DNA damage, probably by Atm or ATR. The PWWP2B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q26. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4. % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.,PWWP domain-containing protein 2B

Poids moléculaire: observerd band 64kDa

ID gène: 170394

UniProt: Q6NUJ5