R-Spondin 3 anticorps
Aperçu rapide pour R-Spondin 3 anticorps (ABIN7231194)
Antigène
Voir toutes R-Spondin 3 (RSPO3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit Anti-RSPO3 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of RSPO3 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human RSPO3 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- R-Spondin 3 (RSPO3)
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Autre désignation
- RSPO3
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Sujet
- Protein with TSP type-1 repeat, hPWTSR, Roof plate-specific spondin-3, hRspo3, Thrombospondin type-1 domain-containing protein 2RSPO3 belongs to the R-spondin family. The encoded protein plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. Genome-wide association studies suggest a correlation of RSPO3 with bone mineral density and risk of fracture. RSPO3 may be involved in tumor development.
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Poids moléculaire
- 29kD
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ID gène
- 84870
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UniProt
- Q9BXY4
Antigène
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