RASIP1 anticorps (AA 620-700)
Aperçu rapide pour RASIP1 anticorps (AA 620-700) (ABIN7230920)
Antigène
Voir toutes RASIP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 620-700
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Fonction
- RAIN Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of RAIN protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human RAIN protein at AA range: 620-700
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RASIP1 (Ras Interacting Protein 1 (RASIP1))
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Autre désignation
- RAIN
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Sujet
- Rabbit Anti-RAIN Polyclonal Antibody,Ras-interacting protein 1, Rain,Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.,RAIN
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Poids moléculaire
- observerd band 105kDa
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ID gène
- 54922
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UniProt
- Q5U651
Antigène
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