RASIP1 anticorps
Aperçu rapide pour RASIP1 anticorps (ABIN7269872)
Antigène
Voir toutes RASIP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RASIP1 Rabbit pAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human RASIP1.
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RASIP1 (Ras Interacting Protein 1 (RASIP1))
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Autre désignation
- RASIP1
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Sujet
- Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells (By similarity. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.,RAIN,RASIP1,G protein signaling,G protein signaling_Small G proteins,Signal Transduction,RASIP1
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ID gène
- 54922
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UniProt
- Q5U651
Antigène
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