RASIP1 anticorps (AA 620-700)

N° du produit ABIN7230920

Cet anticorps anti-RASIP1 Polyclonal Lapin (ABIN7230920) détecte spécifiquement RASIP1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour RASIP1 anticorps (AA 620-700) (ABIN7230920)

Antigène: RASIP1 (Ras Interacting Protein 1 (RASIP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASIP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RASIP1 anticorps

Épitope: AA 620-700

Fonction: Rabbit Anti-RAIN Polyclonal Antibody

Specificité: The antibody detects endogenous levels of RAIN protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human RAIN protein at AA range: 620-700

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RASIP1

Antigène: RASIP1 (Ras Interacting Protein 1 (RASIP1))

Autre désignation: RAIN

Sujet: Ras-interacting protein 1, RainRequired for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.

Poids moléculaire: 105kD

ID gène: 54922

UniProt: Q5U651