RAMP2 anticorps
Aperçu rapide pour RAMP2 anticorps (ABIN7230928)
Antigène
Voir toutes RAMP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- RAMP2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of RAMP2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human RAMP2 protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RAMP2 (Receptor (G Protein-Coupled) Activity Modifying Protein 2 (RAMP2))
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Autre désignation
- RAMP2
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Sujet
- Rabbit Anti-RAMP2 Polyclonal Antibody,Receptor activity-modifying protein 2, Calcitonin-receptor-like receptor activity-modifying protein 2, CRLR activity-modifying protein 2,The protein encoded by RAMP2 gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.,RAMP2
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Poids moléculaire
- observerd band 19kDa
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ID gène
- 10266
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UniProt
- O60895
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Pathways
- cAMP Metabolic Process, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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