RGS17 anticorps (AA 70-150)
Aperçu rapide pour RGS17 anticorps (AA 70-150) (ABIN7231022)
Antigène
Voir toutes RGS17 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 70-150
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Fonction
- Rabbit Anti-RGS17 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of RGS17 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- Synthesized peptide derived from part region of human RGS17 protein at AA range: 70-150
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
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Autre désignation
- RGS17
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Sujet
- Regulator of G-protein signaling 17, RGS17RGS17 (Regulator Of G Protein Signaling 17) encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
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Poids moléculaire
- 23kD
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ID gène
- 26575
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UniProt
- Q9UGC6
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Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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