RGS4 anticorps (AA 80-160)
Aperçu rapide pour RGS4 anticorps (AA 80-160) (ABIN7231032)
Antigène
Voir toutes RGS4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 80-160
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Fonction
- RGS4 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of RGS4 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human RGS4 protein at AA range: 80-160
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RGS4 (Regulator of G-Protein Signaling 4 (RGS4))
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Autre désignation
- RGS4
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Sujet
- Rabbit Anti-RGS4 Polyclonal Antibody,Regulator of G-protein signaling 4, RGP4, RGS4,RGS4 (Regulator Of G Protein Signaling 4) is a Protein Coding gene. Diseases associated with RGS4 include Schizophrenia 9 and Schizophrenia. Among its related pathways are Signaling by GPCR and ADP signalling through P2Y purinoceptor 12. Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for RGS4.,RGS4
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Poids moléculaire
- observerd band 22kDa
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ID gène
- 5999
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UniProt
- P49798
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Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Antigène
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