S100A12 anticorps (AA 290-370)
Aperçu rapide pour S100A12 anticorps (AA 290-370) (ABIN7229764)
Antigène
Voir toutes S100A12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 290-370
-
Fonction
- Rabbit Anti-MRP6 Polyclonal Antibody
-
Specificité
- The antibody detects endogenous levels of MRP6 protein
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogène
- Synthesized peptide derived from part region of human MRP6 protein at AA range: 290-370
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
Agent conservateur
- ProClin
-
Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
Date de péremption
- 12 months
-
-
- S100A12 (S100 Calcium Binding Protein A12 (S100A12))
-
Autre désignation
- MRP6
-
Sujet
- Multidrug resistance-associated protein 6, ATP-binding cassette sub-family C member 6, Anthracycline resistance-associated protein, Multi-specific organic anion transporter E, MOAT-EABCC6 (ATP Binding Cassette Subfamily C Member 6) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. The protein encoded by ABCC6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in ABCC6 cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for ABCC6.
-
Poids moléculaire
- 165kD
-
ID gène
- 368
-
UniProt
- O95255
-
Pathways
- Toll-Like Receptors Cascades, S100 Proteins
Antigène
-