Sclerostin anticorps (AA 130-210)

N° du produit ABIN7222960

L’anticorps anti-Sclerostin Polyclonal Lapin est utilisé pour la détection de Sclerostin dans des échantillons de Humain. Il a été validé pour WB et ELISA.

Aperçu rapide pour Sclerostin anticorps (AA 130-210) (ABIN7222960)

Antigène: Sclerostin (SOST)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Sclerostin est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Sclerostin anticorps

Épitope: AA 130-210

Fonction: Sclerostin Polyclonal Antibody

Specificité: Sclerostin Polyclonal Antibody detects endogenous levels of Sclerostin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the C-terminal region of human Sclerostin at AA range: 130-210

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Sclerostin

Antigène: Sclerostin (SOST)

Autre désignation: Sclerostin

Sujet: Rabbit Anti-Sclerostin Polyclonal Antibody,SOST, Sclerostin,Sclerostin (SOST) is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in SOST are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of SOST, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.,Sclerostin

Poids moléculaire: observerd band 26kDa

ID gène: 50964

UniProt: Q9BQB4