SCRIB anticorps

N° du produit ABIN7231292

L’anticorps anti-SCRIB Polyclonal Lapin est utilisé pour la détection de SCRIB dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour SCRIB anticorps (ABIN7231292)

Antigène: SCRIB (Scribbled Homolog (SCRIB))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCRIB est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SCRIB anticorps

Fonction: Rabbit Anti-SCRIB Polyclonal Antibody

Specificité: The antibody detects endogenous levels of SCRIB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human SCRIB protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SCRIB

Antigène: SCRIB (Scribbled Homolog (SCRIB))

Autre désignation: SCRIB

Sujet: Protein scribble homolog, Scribble, hScrib, Protein LAP4SCRIB gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Poids moléculaire: 179kD

ID gène: 23513

UniProt: Q14160

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization