Septin 5 anticorps (AA 180-260)

N° du produit ABIN7223244

L’anticorps Lapin Polyclonal anti-Septin 5 a été validé pour WB et ELISA. Il convient pour détecter Septin 5 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour Septin 5 anticorps (AA 180-260) (ABIN7223244)

Antigène: Septin 5 (SEPT5)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Septin 5 anticorps

Épitope: AA 180-260

Fonction: Septin 5 Polyclonal Antibody

Specificité: Septin 5 Polyclonal Antibody detects endogenous levels of Septin 5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogène: Synthesized peptide derived from the Internal region of human Septin 5 at AA range: 180-260

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur Septin 5

Antigène: Septin 5 (SEPT5)

Autre désignation: Septin 5

Sujet: Rabbit Anti-Septin 5 Polyclonal Antibody,SEPT5, PNUTL1, Septin-5, Cell division control-related protein 1, CDCrel-1, Peanut-like protein 1,SEPT5 (septin 5) is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. SEPT5 is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and SEPT5 has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB, platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.,Septin-5

Poids moléculaire: observerd band 42kDa

ID gène: 5413

UniProt: Q99719

Pathways: Synaptic Vesicle Exocytosis