Serotonin Receptor 1E anticorps (AA 70-150)

N° du produit ABIN7217098

L’anticorps anti-Serotonin Receptor 1E Polyclonal Lapin est utilisé pour la détection de Serotonin Receptor 1E dans des échantillons de Humain. Il a été validé pour ELISA, IHC et IF.

Aperçu rapide pour Serotonin Receptor 1E anticorps (AA 70-150) (ABIN7217098)

Antigène: Serotonin Receptor 1E (HTR1E)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 1E est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Serotonin Receptor 1E anticorps

Épitope: AA 70-150

Fonction: Rabbit Anti-SR-1E Polyclonal Antibody

Specificité: SR-1E Polyclonal Antibody detects endogenous levels of SR-1E protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human SR-1E at AA range: 70-150

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF/ICC1:50-300,ELISA 1:2000-20000,IHC 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Serotonin Receptor 1E

Antigène: Serotonin Receptor 1E (HTR1E)

Autre désignation: SR-1E

Sujet: HTR1E, 5-hydroxytryptamine receptor 1E, 5-HT-1E, 5-HT1E, S31, Serotonin receptor 1EHTR1E (5-Hydroxytryptamine Receptor 1E) is a Protein Coding gene. Diseases associated with HTR1E include attention deficit-hyperactivity disorder. Among its related pathways are Signaling by GPCR and cAMP signaling pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and serotonin binding. An important paralog of this gene is HTR1F. G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Serotonin 5-ht1E receptors are primarily located in the frontal cortex, caudate putamen, claustrum, hippocampus, and amygdala. The human 5-ht1E receptor gene has been localized to chromosome 6 (6q14-q15), the receptor is closely related to the serotonin 5-HT1F receptor.

Poids moléculaire: 42kD

ID gène: 3354

UniProt: P28566

Pathways: Signalistation JAK/STAT, cAMP Metabolic Process