SH3BP2 anticorps (AA 210-290)
Aperçu rapide pour SH3BP2 anticorps (AA 210-290) (ABIN7227094)
Antigène
Voir toutes SH3BP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 210-290
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Fonction
- 3BP2 Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of 3BP2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human 3BP2 protein at AA range: 210-290
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SH3BP2 (SH3-Domain Binding Protein 2 (SH3BP2))
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Autre désignation
- 3BP2
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Sujet
- Rabbit Anti-3BP2 Polyclonal Antibody,SH3 domain-binding protein 2, 3BP-2,The protein encoded by SH3BP2 has an N-terminal pleckstrin homology (PH) domain, an SH3-binding proline-rich region, and a C-terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases , and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T, natural killer (NK), and basophilic cells. Mutations in SH3BP2 result in cherubism. Multiple transcript variants encoding different isoforms have been found for SH3BP2.,3BP2
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ID gène
- 6452
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UniProt
- P78314
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Pathways
- TCR Signaling
Antigène
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