SOCS7 anticorps

N° du produit ABIN7231442

Cet anticorps Lapin Polyclonal détecte spécifiquement SOCS7 dans ELISA et WB. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour SOCS7 anticorps (ABIN7231442)

Antigène: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS7 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-SOCS7 anticorps

Fonction: Rabbit Anti-SOCS7 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of SOCS7 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human SOCS7 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SOCS7

Antigène: SOCS7 (Suppressor of Cytokine Signaling 7 (SOCS7))

Autre désignation: SOCS7

Sujet: Suppressor of cytokine signaling 7, SOCS-7, Nck, Ash and phospholipase C gamma-binding protein, Nck-associated protein 4, NAP-4SOCS7 (Suppressor Of Cytokine Signaling 7) is a Protein Coding gene. Among its related pathways are Jak-STAT signaling pathway (KEGG) and Prolactin Signaling Pathway. Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Poids moléculaire: 63kD

ID gène: 30837

UniProt: O14512