TJP3 anticorps

N° du produit ABIN7232248

Cet anticorps anti-TJP3 Polyclonal Lapin (ABIN7232248) détecte spécifiquement TJP3 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Singe.

Aperçu rapide pour TJP3 anticorps (ABIN7232248)

Antigène: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Reactivité: Humain, Souris, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TJP3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TJP3 anticorps

Fonction: Rabbit Anti-ZO3 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of ZO3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human ZO3 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TJP3

Antigène: TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))

Autre désignation: ZO3

Sujet: Tight junction protein ZO-3, Tight junction protein 3, Zona occludens protein 3, Zonula occludens protein 3The protein encoded by TJP3 is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by TJP3 plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. TJP3 has a partial pseudogene on chromosome 1.

Poids moléculaire: 102kD

ID gène: 27134

UniProt: O95049