Topoisomerase I anticorps (Internal Region)
Aperçu rapide pour Topoisomerase I anticorps (Internal Region) (ABIN7224740)
Antigène
Voir toutes Topoisomerase I (TOP1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Fonction
- Topo I Polyclonal Antibody
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Specificité
- Topo I Polyclonal Antibody detects endogenous levels of Topo I protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human Topo I
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
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Autre désignation
- Topo I
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Sujet
- Rabbit Anti-Topo I Polyclonal Antibody,TOP1, DNA topoisomerase 1, DNA topoisomerase I,TOP1 (topoisomerase (DNA) I) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. TOP1 is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.,DNA topoisomerase 1
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Poids moléculaire
- observerd band 90kDa
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ID gène
- 7150
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UniProt
- P11387
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Pathways
- Caspase Cascade in Apoptosis, Stem Cell Maintenance
Antigène
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