TOP3A anticorps (AA 350-430)
Aperçu rapide pour TOP3A anticorps (AA 350-430) (ABIN7226600)
Antigène
Voir toutes TOP3A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 350-430
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Fonction
- Topo IIIα Polyclonal Antibody
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Specificité
- Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human Topo IIIalpha at AA range: 350-430
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TOP3A (Topoisomerase (DNA) III alpha (TOP3A))
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Autre désignation
- Topo IIIalpha
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Sujet
- Rabbit Anti-Topo IIIα Polyclonal Antibody,TOP3A, TOP3, DNA topoisomerase 3-alpha, DNA topoisomerase III alpha,TOP3A(topoisomerase(DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.,DNA topoisomerase 3-alpha
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Poids moléculaire
- observerd band 115kDa
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ID gène
- 7156
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UniProt
- Q13472
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Pathways
- Réparation de l'ADN
Antigène
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