TOP3A anticorps (AA 350-430)

N° du produit ABIN7226600

L’anticorps anti-TOP3A Polyclonal Lapin est utilisé pour la détection de TOP3A dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour TOP3A anticorps (AA 350-430) (ABIN7226600)

Antigène: TOP3A (Topoisomerase (DNA) III alpha (TOP3A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOP3A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TOP3A anticorps

Épitope: AA 350-430

Fonction: Rabbit Anti-Topo IIIα Polyclonal Antibody

Specificité: Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from the Internal region of human Topo IIIalpha at AA range: 350-430

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TOP3A

Antigène: TOP3A (Topoisomerase (DNA) III alpha (TOP3A))

Autre désignation: Topo IIIalpha

Sujet: TOP3A, TOP3, DNA topoisomerase 3-alpha, DNA topoisomerase III alphaTOP3A(topoisomerase(DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire: 115kD

ID gène: 7156

UniProt: Q13472

Pathways: Réparation de l'ADN