TLE4 anticorps (AA 130-210)
Aperçu rapide pour TLE4 anticorps (AA 130-210) (ABIN7217332)
Antigène
Voir toutes TLE4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 130-210
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Fonction
- TLE4 Polyclonal Antibody
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Specificité
- TLE4 Polyclonal Antibody detects endogenous levels of TLE4 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from the Internal region of human TLE4 at AA range: 130-210
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TLE4 (Transducin-like Enhancer Protein 4 (TLE4))
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Autre désignation
- TLE4
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Sujet
- Rabbit Anti-TLE4 Polyclonal Antibody,TLE4, KIAA1261, Transducin-like enhancer protein 4,TLE4 (Transducin Like Enhancer Of Split 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by NOTCH1. Gene Ontology (GO) annotations related to this gene include chromatin binding and transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. An important paralog of this gene is AES. Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity).,Transducin-like enhancer protein 4
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Poids moléculaire
- observerd band 83kDa
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ID gène
- 7091
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UniProt
- Q04727
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Pathways
- Signalisation WNT
Antigène
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