TSEN2 anticorps

N° du produit ABIN7231306

Cet anticorps anti-TSEN2 Polyclonal Lapin (ABIN7231306) détecte spécifiquement TSEN2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TSEN2 anticorps (ABIN7231306)

Antigène: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSEN2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TSEN2 anticorps

Fonction: Rabbit Anti-SEN2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of SEN2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human SEN2 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TSEN2

Antigène: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Autre désignation: SEN2

Sujet: TRNA-splicing endonuclease subunit Sen2, tRNA-intron endonuclease Sen2, HsSen2TSEN2 (TRNA Splicing Endonuclease Subunit 2) is a Protein Coding gene. Diseases associated with TSEN2 include Pontocerebellar Hypoplasia Type 2B and Pontocerebellar Hypoplasia, Type 2E. Among its related pathways are Gene Expression and tRNA processing. TSEN2 encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in TSEN2 have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for TSEN2.

Poids moléculaire: 51kD

ID gène: 80746

UniProt: Q8NCE0

Pathways: Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha