TNNI2 anticorps (pSer22)
Aperçu rapide pour TNNI2 anticorps (pSer22) (ABIN7218820)
Antigène
Voir toutes TNNI2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer22
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Fonction
- Troponin I-C (phospho Ser22/S23) Polyclonal Antibody
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Specificité
- Phospho-Troponin I-C (S22/S23) Polyclonal Antibody detects endogenous levels of Troponin I-C protein only when phosphorylated at S22/S23.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogène
- Synthesized peptide derived from human Troponin I-C Phospho-Ser22/S23
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TNNI2 (Fast Skeletal Troponin I (TNNI2))
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Autre désignation
- Troponin I-C
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Sujet
- Rabbit Anti-Troponin I-C (phospho Ser22/S23) Polyclonal Antibody,TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I,Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).,Troponin I cardiac muscle
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Poids moléculaire
- observerd band 28kDa
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ID gène
- 7137
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UniProt
- P19429
Antigène
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