UIMC1 anticorps

N° du produit ABIN7232032

L’anticorps Lapin Polyclonal anti-UIMC1 a été validé pour WB et ELISA. Il convient pour détecter UIMC1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour UIMC1 anticorps (ABIN7232032)

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UIMC1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-UIMC1 anticorps

Fonction: UIMC1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of UIMC1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogène: Synthesized peptide derived from part region of human UIMC1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Commentaires:

Primary Antibody

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Détails sur UIMC1

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Autre désignation: UIMC1

Sujet: Rabbit Anti-UIMC1 Polyclonal Antibody,BRCA1-A complex subunit RAP80, Receptor-associated protein 80, Retinoid X receptor-interacting protein 110, Ubiquitin interaction motif-containing protein 1,UIMC1 (Ubiquitin Interaction Motif Containing 1) is a Protein Coding gene. Among its related pathways are DNA Damage and DNA Double Strand Break Response. UIMC1 encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.,UIMC1

Poids moléculaire: observerd band 79kDa

ID gène: 51720

UniProt: Q96RL1

Pathways: Réparation de l'ADN, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus