UIMC1 anticorps

N° du produit ABIN7232032

L’anticorps anti-UIMC1 Polyclonal Lapin est utilisé pour la détection de UIMC1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour UIMC1 anticorps (ABIN7232032)

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UIMC1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-UIMC1 anticorps

Fonction: Rabbit Anti-UIMC1 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of UIMC1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human UIMC1 protein

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur UIMC1

Antigène: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Autre désignation: UIMC1

Sujet: BRCA1-A complex subunit RAP80, Receptor-associated protein 80, Retinoid X receptor-interacting protein 110, Ubiquitin interaction motif-containing protein 1UIMC1 (Ubiquitin Interaction Motif Containing 1) is a Protein Coding gene. Among its related pathways are DNA Damage and DNA Double Strand Break Response. UIMC1 encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 79kD

ID gène: 51720

UniProt: Q96RL1

Pathways: Réparation de l'ADN, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus