XDH anticorps
Aperçu rapide pour XDH anticorps (ABIN7232182)
Antigène
Voir toutes XDH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- XDH Polyclonal Antibody
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Specificité
- The antibody detects endogenous levels of XDH protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogène
- Synthesized peptide derived from part region of human XDH protein
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Isotype
- IgG
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Commentaires
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- XDH (Xanthine Dehydrogenase (XDH))
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Autre désignation
- XDH
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Sujet
- Rabbit Anti-XDH Polyclonal Antibody,Xanthine dehydrogenase/oxidase, Xanthine oxidoreductase, XOR,XDH (Xanthine Dehydrogenase) is a Protein Coding gene. Diseases associated with XDH include Xanthinuria, Type I and Xanthinuria. Among its related pathways are Doxorubicin Pathway, Pharmacokinetics and Metabolism. XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. XDH can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in XDH cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.,XDH
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Poids moléculaire
- observerd band 146kDa
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ID gène
- 7498
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UniProt
- P47989
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Pathways
- Positive Regulation of Endopeptidase Activity
Antigène
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