GLI1 anticorps (AA 460-490)

N° du produit ABIN7228664

Cet anticorps Lapin Polyclonal détecte spécifiquement GLI1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour GLI1 anticorps (AA 460-490) (ABIN7228664)

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-GLI1 anticorps

Épitope: AA 460-490

Fonction: Rabbit Anti-GLI-1 Polyclonal Antibody

Specificité: This antibody detects endogenous levels of GLI-1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human GLI-1 protein at AA range: 460-490

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GLI1

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Autre désignation: GLI-1

Sujet: Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLIGLI1 encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 120kD

ID gène: 2735

UniProt: P08151

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis