ABHD12 anticorps (AA 110-250)
Aperçu rapide pour ABHD12 anticorps (AA 110-250) (ABIN7265355)
Antigène
Voir toutes ABHD12 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 110-250
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Fonction
- ABHD12 Rabbit pAb
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Séquence
- YFIDLKKPQD QGLNHTCNYY LQPEEDVTIG VWHTVPAVWW KNAQGKDQMW YEDALASSHP IILYLHGNAG TRGGDHRVEL YKVLSSLGYH VVTFDYRGWG DSVGTPSERG MTYDALHVFD WIKARSGDNP VYIWGHSLGT G
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Réactivité croisée
- Humain, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human ABHD12 (NP_056415.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- ABHD12 (Abhydrolase Domain Containing 12 (ABHD12))
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Autre désignation
- ABHD12
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Sujet
- This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011],ABHD12A,BEM46L2,C20orf22,PHARC,dJ965G21.2,ABHD12,ABHD12
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ID gène
- 26090
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UniProt
- Q8N2K0
Antigène
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