BAF53A anticorps

N° du produit ABIN7265387

L’anticorps Lapin Monoclonal anti-BAF53A a été validé pour WB et IHC. Il convient pour détecter BAF53A dans des échantillons de Humain.

Aperçu rapide pour BAF53A anticorps (ABIN7265387)

Antigène: BAF53A (Actin-Like 6A (BAF53A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp BAF53A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-BAF53A anticorps

Fonction: ACTL6A Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human ACTL6A

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur BAF53A

Antigène: BAF53A (Actin-Like 6A (BAF53A))

Autre désignation: ACTL6A

Sujet: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008],ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K,Cell Biology & Developmental Biology,Chromatin Remodeling,Cytoskeleton,Cytoskeleton_Microfilaments,Epigenetics & Nuclear Signaling,Signal Transduction,ACTL6A

Poids moléculaire: 47kDa

ID gène: 86

UniProt: O96019

Pathways: Chromatin Binding, Photoperiodism