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alpha 2 Macroglobulin anticorps
A2M
Reactivité: Humain
WB, IHC, IF
Hôte: Lapin
Monoclonal
unconjugated
N° du produit ABIN7265558
Détail du produit anti-alpha 2 Macroglobulin anticorps
(cache)
Antigène
Voir toutes alpha 2 Macroglobulin (A2M) Anticorps
alpha 2 Macroglobulin (A2M)
(alpha-2-Macroglobulin (A2M))
Reactivité
Toutes les réactivités sur alpha 2 Macroglobulin Anticorps
Humain
Hôte
Toutes les hôtes sur alpha 2 Macroglobulin Anticorps
Lapin
Clonalité
Toutes les clonalités sur alpha 2 Macroglobulin Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers alpha 2 Macroglobulin Anticorps
Cet anticorp alpha 2 Macroglobulin est non-conjugé
Application
Tous les applications à travers alpha 2 Macroglobulin Anticorps.
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Fonction
Alpha-2-Macroglobulin (A2M) Rabbit mAb
Réactivité croisée
Humain, Souris, Rat
Attributs du produit
Monoclonal Antibodies
Purification
Affinity purification
Immunogène
A synthesized peptide derived from human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M))
Isotype
IgG
Top Product
Discover our top product A2M Anticorps primaire
Alternatives
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Information d'application
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Indications d'application
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur alpha 2 Macroglobulin
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Antigène
alpha 2 Macroglobulin (A2M)
(alpha-2-Macroglobulin (A2M))
Autre désignation
A2M (A2M Produits )
Synonymes
anticorps A2MD, anticorps CPAMD5, anticorps FWP007, anticorps S863-7, anticorps A2MAC1, anticorps A2m1, anticorps A2maa, anticorps Mam, anticorps A2mp, anticorps A2M, anticorps LOC733429, anticorps endod, anticorps cpamd5, anticorps fwp007, anticorps s863-7, anticorps a2mb, anticorps endodermin, anticorps Alpha-2-M, anticorps alpha-2-macroglobulin, anticorps pregnancy-zone protein L homeolog, anticorps alpha-2-macroglobulin S homeolog, anticorps pregnancy zone protein, anticorps alpha-2-macroglobulin-like, anticorps A2M, anticorps A2m, anticorps LOC477699, anticorps pzp.L, anticorps AZL_c00450, anticorps LOC100349077, anticorps a2m, anticorps LOC100061656, anticorps LOC100090399, anticorps a2m.S, anticorps LOC100469973, anticorps LOC100595735, anticorps PZP, anticorps LOC100353095, anticorps LOC101122940, anticorps LOC101801552, anticorps LOC100911545
Sujet
The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016],A2MD, CPAMD5, FWP007, S863-7,Blood,Blood_Serum Proteins,Cardiovascular,Cell Biology & Developmental Biology,Ubiquitin,A2M
Poids moléculaire
163kDa
ID gène
2
UniProt
P01023
Pathways
Lipid Metabolism
Vus récemment
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