ANKRD15 anticorps (AA 900-1000)

N° du produit ABIN7265613

Cet anticorps anti-ANKRD15 est un anticorps Lapin Polyclonal détectant ANKRD15 dans WB et IF. Adapté pour Humain.

Aperçu rapide pour ANKRD15 anticorps (AA 900-1000) (ABIN7265613)

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANKRD15 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-ANKRD15 anticorps

Épitope: AA 900-1000

Fonction: KANK1 Rabbit pAb

Séquence: GNYLGYTCKC GGLQSGSPLS SQTSQPEQEV GTSEGKPISS LDAFPTQEGT LSPVNLTDDQ IAAGLYACTN NESTLKSIMK KKDGNKDSNG AKKNLQFVGI N

Réactivité croisée: Humain, Souris

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 900-1000 of human KANK1 (NP_055973.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur ANKRD15

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Autre désignation: KANK1

Sujet: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5,9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.,KANK1,ANKRD15,CPSQ2,KANK,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,KANK1

Poids moléculaire: 129kDa/147kDa

ID gène: 23189

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization