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BBS7 anticorps (AA 1-270)

L’anticorps Lapin Polyclonal anti-BBS7 a été validé pour WB, IHC et IF. Il convient pour détecter BBS7 dans des échantillons de Humain.
N° du produit ABIN7265825

Aperçu rapide pour BBS7 anticorps (AA 1-270) (ABIN7265825)

Antigène

Voir toutes BBS7 Anticorps
BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Reactivité

  • 26
  • 3
  • 2
Humain

Hôte

  • 22
  • 3
  • 1
Lapin

Clonalité

  • 24
  • 2
Polyclonal

Conjugué

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp BBS7 est non-conjugé

Application

  • 21
  • 16
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Épitope

    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-270

    Fonction

    BBS7 Rabbit pAb

    Séquence

    MDLILNRMDY LQVGVTSQKT MKLIPASRHR ATQKVVIGDH DGVVMCFGMK KGEAAAVFKT LPGPKIARLE LGGVINTPQE KIFIAAASEI RGFTKRGKQF LSFETNLTES IKAMHISGSD LFLSASYIYN HYCDCKDQHY YLSGDKINDV ICLPVERLSR ITPVLACQDR VLRVLQGSDV MYAVEVPGPP TVLALHNGNG GDSGEDLLFG TSDGKLALIQ ITTSKPVRKW EIQNEKKRGG ILCIDSFDIV GDGVKDLLVG RDDGMVEVYS

     Réactivité croisée

    Humain, Souris, Rat

    Attributs du produit

    Polyclonal Antibodies

    Purification

    Affinity purification

    Immunogène

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human BBS7 (NP_060660.2).

    Isotype

    IgG
  • Indications d'application

    WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

    Autre désignation

    BBS7

    Sujet

    This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy, however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014],BBS2L1,BBS7,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Endocrine & Metabolism,Neuroscience,BBS7

    Poids moléculaire

    75kDa/80kDa

    ID gène

    55212

    UniProt

    Q8IWZ6

    Pathways

    Signalisation Hedgehog
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