CARD11 anticorps

N° du produit ABIN7266125

L’anticorps Lapin Monoclonal anti-CARD11 a été validé pour WB, IHC et IF. Il convient pour détecter CARD11 dans des échantillons de Humain.

Aperçu rapide pour CARD11 anticorps (ABIN7266125)

Antigène: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CARD11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-CARD11 anticorps

Fonction: CARD11 Rabbit mAb

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human CARD11

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CARD11

Antigène: CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))

Autre désignation: CARD11

Sujet: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008],BENTA, BIMP3, CARMA1, IMD11, PPBL,Apoptosis,Apoptosis_Caspases,B Cell Receptor Signaling Pathway,Cancer,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Signal Transduction,T Cell Receptor Signaling Pathway,CARD11

Poids moléculaire: 133kDa

ID gène: 84433

UniProt: Q9BXL7

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, BCR Signaling