CENPE anticorps (AA 2542-2701)

N° du produit ABIN7266274

Cet anticorps Lapin Polyclonal détecte spécifiquement CENPE dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour CENPE anticorps (AA 2542-2701) (ABIN7266274)

Antigène: CENPE (Centromere Protein E, 312kDa (CENPE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPE est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CENPE anticorps

Épitope: AA 2542-2701

Fonction: CENPE Rabbit pAb

Séquence: ALILKSEHIR LEKEISKLKQ QNEQLIKQKN ELLSNNQHLS NEVKTWKERT LKREAHKQVT CENSPKSPKV TGTASKKKQI TPSQCKERNL QDPVPKESPK SCFFDSRSKS LPSPHPVRYF DNSSLGLCPE VQNAGAESVD SQPGPWHASS GKDVPECKTQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 2542-2701 of human CENPE (NP_001804.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CENPE

Antigène: CENPE (Centromere Protein E, 312kDa (CENPE))

Autre désignation: CENPE

Sujet: Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.,CENPE,CENP-E,KIF10,MCPH13,PPP1R61,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centromere,CENPE

Poids moléculaire: 301kDa/312kDa/316kDa

ID gène: 1062

UniProt: Q02224

Pathways: M Phase, Maintenance of Protein Location