CENPE anticorps (AA 2542-2701)

N° du produit ABIN7266274

Détail du produit anti-CENPE anticorps

Antigène: CENPE (Centromere Protein E, 312kDa (CENPE))

Épitope: AA 2542-2701

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPE est non-conjugé

Application: Western Blotting (WB)

Fonction: CENPE Rabbit pAb

Séquence: ALILKSEHIR LEKEISKLKQ QNEQLIKQKN ELLSNNQHLS NEVKTWKERT LKREAHKQVT CENSPKSPKV TGTASKKKQI TPSQCKERNL QDPVPKESPK SCFFDSRSKS LPSPHPVRYF DNSSLGLCPE VQNAGAESVD SQPGPWHASS GKDVPECKTQ

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 2542-2701 of human CENPE (NP_001804.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CENPE

Antigène: CENPE (Centromere Protein E, 312kDa (CENPE))

Autre désignation: CENPE (CENPE Produits)

Synonymes: anticorps CENP-E, anticorps KIF10, anticorps PPP1R61, anticorps 312kDa, anticorps AU019344, anticorps BC049989, anticorps C530022J18, anticorps Kif10, anticorps CENPE, anticorps kif10, anticorps cenp-E, anticorps XCENP-E, anticorps wu:fc06a10, anticorps zgc:152925, anticorps centromere protein E, anticorps centromere protein E, 312kDa, anticorps CENPE, anticorps Cenpe, anticorps cenpe

Sujet: Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms.,CENPE,CENP-E,KIF10,MCPH13,PPP1R61,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centromere,CENPE

Poids moléculaire: 301kDa/312kDa/316kDa

ID gène: 1062

UniProt: Q02224

Pathways: M Phase, Maintenance of Protein Location