CHM anticorps

N° du produit ABIN7266354

Cet anticorps anti-CHM est un anticorps Lapin Monoclonal détectant CHM dans WB. Adapté pour Humain.

Aperçu rapide pour CHM anticorps (ABIN7266354)

Antigène: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CHM est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHM anticorps

Fonction: CHM Rabbit mAb

Réactivité croisée: Humain

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human CHM.

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CHM

Antigène: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Autre désignation: CHM

Sujet: This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia, also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene.,CHM, DXS540, GGTA, HSD-32, REP-1, TCD, CHM, Rab escort protein 1,Signal Transduction,Neuroscience,CHM

Poids moléculaire: 95kDa

ID gène: 1121

UniProt: P24386

Pathways: Sensory Perception of Sound