CBX3 anticorps (pSer83)
Aperçu rapide pour CBX3 anticorps (pSer83) (ABIN7266358)
Antigène
Voir toutes CBX3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer83
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Fonction
- Phospho-HP1 gamma/CBX3-S83 Rabbit pAb
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Phosphorylated Antibodies
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Purification
- Affinity purification
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Immunogène
- A phospho specific peptide corresponding to residues surrounding S83 of human HP1 gamma/CBX3
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- CBX3 (Chromobox Homolog 3 (CBX3))
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Autre désignation
- CBX3
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Sujet
- At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.,CBX3,HECH,HP1-GAMMA,HP1Hs-gamma,Epigenetics & Nuclear Signaling,Protein phosphorylation,CBX3
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Poids moléculaire
- 20kDa
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ID gène
- 11335
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UniProt
- Q13185
Antigène
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