Girdin anticorps (AA 1571-1870)
Aperçu rapide pour Girdin anticorps (AA 1571-1870) (ABIN7266446)
Antigène
Voir toutes Girdin (CCDC88A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1571-1870
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Fonction
- CCDC88A Rabbit pAb
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Séquence
- DDSSTGSRVH ASRPASLDSG RTSTSNSNNN ASLHEVKAGA VNNQSRPQSH SSGEFSLLHD HEAWSSSGSS PIQYLKRQTR SSPVLQHKIS ETLESRHHKI KTGSPGSEVV TLQQFLEESN KLTSVQIKSS SQENLLDEVM KSLSVSSDFL GKDKPVSCGL ARSVSGKTPG DFYDRRTTKP EFLRPGPRKT EDTYFISSAG KPTPGTQGKI KLVKESSLSR QSKDSNPYAT LPRASSVIST AEGTTRRTSI HDFLTKDSRL PISVDSPPAA ADSNTTAASN VDKVQESRNS KSRSREQQSS
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Réactivité croisée
- Humain
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 1571-1870 of human CCDC88A (NP_001129069.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
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Autre désignation
- CCDC88A
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Sujet
- This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,CCDC88A,APE,GIRDIN,GIV,GRDN,HkRP1,KIAA1212,PEHO,girdin,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microtubules,Neuroscience,CCDC88A
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Poids moléculaire
- 207kDa/212kDa/215kDa/216kDa
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ID gène
- 55704
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UniProt
- Q3V6T2
Antigène
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