DDB2 anticorps

N° du produit ABIN7266674

L’anticorps Lapin Monoclonal anti-DDB2 a été validé pour WB. Il convient pour détecter DDB2 dans des échantillons de Humain.

Aperçu rapide pour DDB2 anticorps (ABIN7266674)

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp DDB2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DDB2 anticorps

Fonction: DDB2 Rabbit mAb

Réactivité croisée: Humain, Souris

Attributs du produit: Monoclonal Antibodies

Purification: Affinity purification

Immunogène: A synthesized peptide derived from human DDB2

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DDB2

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Autre désignation: DDB2

Sujet: This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],DDBB, UV-DDB2, XPE,Cell Biology & Developmental Biology,DNA Damage & Repair,Epigenetics & Nuclear Signaling,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,DDB2

Poids moléculaire: 45kDa

ID gène: 1643

UniProt: Q92466

Pathways: Réparation de l'ADN