DRAP1 anticorps (AA 50-150)

N° du produit ABIN7266844

Cet anticorps Lapin Polyclonal détecte spécifiquement DRAP1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour DRAP1 anticorps (AA 50-150) (ABIN7266844)

Antigène: DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRAP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DRAP1 anticorps

Épitope: AA 50-150

Fonction: DRAP1 Rabbit pAb

Séquence: LKKACQVTQS RNAKTMTTSH LKQCIELEQQ FDFLKDLVAS VPDMQGDGED NHMDGDKGAR RGRKPGSGGR KNGGMGTKSK DKKLSGTDSE QEDESEDTDT D

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 50-150 of human DRAP1 (NP_006433.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DRAP1

Antigène: DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Autre désignation: DRAP1

Sujet: Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008],NC2-alpha,DRAP1,Epigenetics & Nuclear Signaling,Transcription Factors,DRAP1

ID gène: 10589

UniProt: Q14919