DRAP1 anticorps (N-Term)

N° du produit ABIN1538849

Détail du produit anti-DRAP1 anticorps

Antigène: DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Épitope: AA 1-29, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRAP1 est non-conjugé

Application: Western Blotting (WB)

Homologie: B, M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DRAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human DRAP1.

Clone: RB32124

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: DRAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Date de péremption: 6 months

Détails sur DRAP1

Antigène: DRAP1 (DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))

Autre désignation: DRAP1 (DRAP1 Produits)

Synonymes: anticorps fb26e10, anticorps zgc:56003, anticorps zgc:77337, anticorps wu:fb26e10, anticorps DRAP1, anticorps 2310074H19Rik, anticorps NC2-alpha, anticorps DR1-associated protein 1 (negative cofactor 2 alpha), anticorps DR1 associated protein 1, anticorps Dr1 associated protein 1 (negative cofactor 2 alpha), anticorps Dr1 associated protein 1, anticorps drap1, anticorps DRAP1, anticorps Drap1

Sujet: Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex.

Poids moléculaire: 22350

ID gène: 10589

NCBI Accession: NP_006433

UniProt: Q14919