EDARADD anticorps (AA 1-215)

N° du produit ABIN7266900

Cet anticorps anti-EDARADD est un anticorps Lapin Polyclonal détectant EDARADD dans WB. Adapté pour Humain.

Aperçu rapide pour EDARADD anticorps (AA 1-215) (ABIN7266900)

Antigène: EDARADD (EDAR-Associated Death Domain (EDARADD))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDARADD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-EDARADD anticorps

Épitope: AA 1-215

Fonction: EDARADD Rabbit pAb

Séquence: MGLRTTKQMG RGTKAPGHQE DHMVKEPVED TDPSTLSFNM SDKYPIQDTE LPKAEECDTI TLNCPRNSDM KNQGEENGFP DSTGDPLPEI SKDNSCKENC TCSSCLLRAP TISDLLNDQD LLDVIRIKLD PCHPTVKNWR NFASKWGMSY DELCFLEQRP QSPTLEFLLR NSQRTVGQLM ELCRLYHRAD VEKVLRRWVD EEWPKRERGD PSRHF

Réactivité croisée: Humain

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human EDARADD (NP_665860.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur EDARADD

Antigène: EDARADD (EDAR-Associated Death Domain (EDARADD))

Autre désignation: EDARADD

Sujet: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,EDARADD,ECTD11A,ECTD11B,ED3,EDA3,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,EDARADD

Poids moléculaire: 23kDa/24kDa

ID gène: 128178

UniProt: Q8WWZ3

Pathways: Ubiquitin Proteasome Pathway