Ensa anticorps (AA 1-100)
Aperçu rapide pour Ensa anticorps (AA 1-100) (ABIN7266947)
Antigène
Voir toutes Ensa (ENSA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-100
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Fonction
- ENSA Rabbit pAb
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Séquence
- MAGGLGCDVC YWFVEDTQEK EGILPERAEE AKLKAKYPSL GQKPGGSDFL MKRLQKGQKY FDSGDYNMAK AKMKNKQLPS AGPDKNLVTG DHIPTPQDLP
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Réactivité croisée
- Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ENSA (NP_996929.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Ensa (ENSA) (Endosulfine alpha (ENSA))
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Autre désignation
- ENSA
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Sujet
- The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed.,ENSA,ARPP-19e,Neuroscience,ENSA
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Poids moléculaire
- 11kDa/12kDa/13kDa/14kDa/15kDa
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ID gène
- 2029
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UniProt
- O43768
Antigène
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