FCN3 anticorps (AA 13-288)
Aperçu rapide pour FCN3 anticorps (AA 13-288) (ABIN7267202)
Antigène
Voir toutes FCN3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 13-288
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Fonction
- FCN3 Rabbit pAb
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Séquence
- LLLGGPACLK TQEHPSCPGP RELEASKVVL LPSCPGAPGS PGEKGAPGPQ GPPGPPGKMG PKGEPGPRNC RELLSQGATL SGWYHLCLPE GRALPVFCDM DTEGGGWLVF QRRQDGSVDF FRSWSSYRAG FGNQESEFWL GNENLHQLTL QGNWELRVEL EDFNGNRTFA HYATFRLLGE VDHYQLALGK FSEGTAGDSL SLHSGRPFTT YDADHDSSNS NCAVIVHGAW WYASCYRSNL NGRYAVSEAA AHKYGIDWAS GRGVGHPYRR VRMMLR
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 13-288 of human FCN3 (NP_775628.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- FCN3 (Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3))
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Autre désignation
- FCN3
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Sujet
- Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.,FCN3,FCNH,HAKA1,ficolin-3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Immunology & Inflammation,FCN3
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Poids moléculaire
- 31kDa/32kDa
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ID gène
- 8547
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UniProt
- O75636
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Pathways
- Système du Complément
Antigène
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