SIP1 anticorps
Aperçu rapide pour SIP1 anticorps (ABIN7267366)
Antigène
Voir toutes SIP1 (GEMIN2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Gemin 2 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human Gemin 2 .
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
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Autre désignation
- Gemin 2
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Sujet
- This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.,GEMIN2, SIP1, SIP1-delta, gem-associated protein 2,Signal Transduction,Neuroscience,Gemin 2
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Poids moléculaire
- 31kDa
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ID gène
- 8487
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UniProt
- O14893
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Pathways
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
Antigène
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