GLI3 anticorps
Aperçu rapide pour GLI3 anticorps (ABIN7267385)
Antigène
Voir toutes GLI3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Gli3 Rabbit mAb
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human Gli3
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- GLI3 (GLI Family Zinc Finger 3 (GLI3))
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Autre désignation
- GLI3
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Sujet
- This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008],ACLS, GCPS, GLI3-190, GLI3FL, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Hedgehog Signaling Pathway,Neuroscience,Signal Transduction,Stem Cells,Transcription Factors,GLI3
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Poids moléculaire
- 190kDa
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ID gène
- 2737
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UniProt
- P10071
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Pathways
- Signalisation Hedgehog
Antigène
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