GPI anticorps
Aperçu rapide pour GPI anticorps (ABIN7267403)
Antigène
Voir toutes GPI AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- glucose-6-phosphate isomerase Rabbit mAb
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Réactivité croisée
- Humain, Rat
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Attributs du produit
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthesized peptide derived from human Glucose 6 phosphate isomerase
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- GPI (Glucose-6-Phosphate Isomerase (GPI))
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Autre désignation
- GPI
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Sujet
- This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phosphate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],AMF, GNPI, NLK, PGI, PHI, SA-36, SA36,Cancer,Carbohydrate metabolism,Cell Biology & Developmental Biology,Cytokines,Endocrine & Metabolism,Growth factors,Immunology & Inflammation,Neuroscience,Signal Transduction,GPI
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Poids moléculaire
- 63kDa
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ID gène
- 2821
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UniProt
- P06744
Antigène
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