GNRHR anticorps (AA 200-300)
Aperçu rapide pour GNRHR anticorps (AA 200-300) (ABIN7267500)
Antigène
Voir toutes GNRHR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 200-300
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Fonction
- GNRHR Rabbit pAb
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Séquence
- CSFSQWWHQA FYNFFTFSCL FIIPLFIMLI CNAKIIFTLT RVLHQDPHEL QLNQSKNNIP RARLKTLKMT VAFATSFTVC WTPYYVLGIW YWFDPEMLNR L
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Réactivité croisée
- Humain, Souris
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GNRHR (NP_000397.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- GNRHR (Gonadotropin-Releasing Hormone Receptor (GNRHR))
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Autre désignation
- GNRHR
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Sujet
- This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.,GNRHR,GNRHR1,GRHR,HH7,LHRHR,LRHR,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Neuroscience,GNRHR
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Poids moléculaire
- 27kDa/37kDa
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ID gène
- 2798
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UniProt
- P30968
Antigène
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